Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.38 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12147108 | 0.96 | MAPT (0.36) | MAPTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12147806 | 0.85 | GAA (0.39) | MAPTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12787040 | 0.84 | MAPT (0.40) | MAPTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12147824 | 0.83 | GAA (0.38) | MAPTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12846333 | 0.82 | MAPT (0.44) | MAPTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13258578 | 0.82 | GAA (0.36) | MAPTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12761951 | 0.81 | GAA (0.40) | MAPTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13258688 | 0.81 | MAPT (0.39) | MAPTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12147107 | 0.81 | GAA (0.36) | MAPTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12147810 | 0.81 | GAA (0.36) | MAPTGAAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010092030-A1 | TIME-TEMPERATURE INDICATOR BASED ON THIOALKYL AND THIOARYL SUBSTITUTED SPIROAROMATICS | FRESHPOINT HOLDINGS SA (CH) | 2010-08-19 | — | — | WO | disclosed |