Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 10/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL601588 | 0.86 | GPBAR1 (0.57) | GPBAR1 | |
| SCHEMBL13259965 | 0.86 | GPBAR1 (0.54) | GPBAR1 | |
| SCHEMBL13259062 | 0.85 | GPBAR1 (0.73) | GPBAR1 | |
| SCHEMBL603537 | 0.84 | GPBAR1 (0.73) | GPBAR1 | |
| SCHEMBL13259060 | 0.81 | GPBAR1 (0.66) | GPBAR1 | |
| SCHEMBL602777 | 0.78 | GPBAR1 (0.55) | GPBAR1 | |
| SCHEMBL602135 | 0.77 | GPBAR1 (0.65) | GPBAR1 | |
| SCHEMBL13259058 | 0.77 | GPBAR1 (0.52) | GPBAR1 | |
| SCHEMBL13259966 | 0.76 | GPBAR1 (0.59) | GPBAR1 | |
| SCHEMBL601636 | 0.76 | GPBAR1 (0.53) | GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093845-A1 | TRIAZOLE AND IMIDAZOLE DERIVATIVES FOR USE AS TGR5 AGONISTS IN THE TREATMENT OF DIABETES AND OBESITY | EXELIXIS, INC. (US) | 2010-08-19 | — | — | WO | disclosed |