Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL604079 | 0.89 | GPBAR1 (0.56) | GPBAR1NR1H4 | |
| SCHEMBL601070 | 0.88 | GPBAR1 (0.54) | GPBAR1NR1H4 | |
| SCHEMBL13259092 | 0.85 | GPBAR1 (0.50) | GPBAR1NR1H4 | |
| SCHEMBL601617 | 0.83 | GPBAR1 (0.53) | GPBAR1NR1H4 | |
| SCHEMBL604510 | 0.83 | GPBAR1 (0.51) | GPBAR1NR1H4 | |
| SCHEMBL605167 | 0.83 | GPBAR1 (0.52) | GPBAR1NR1H4 | |
| SCHEMBL600984 | 0.82 | GPBAR1 (0.54) | GPBAR1NR1H4 | |
| SCHEMBL13259075 | 0.81 | GPBAR1 (0.70) | GPBAR1 | |
| SCHEMBL603467 | 0.80 | GPBAR1 (0.59) | GPBAR1NR1H4 | |
| SCHEMBL602825 | 0.78 | GPBAR1 (0.52) | GPBAR1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093845-A1 | TRIAZOLE AND IMIDAZOLE DERIVATIVES FOR USE AS TGR5 AGONISTS IN THE TREATMENT OF DIABETES AND OBESITY | EXELIXIS, INC. (US) | 2010-08-19 | — | — | WO | disclosed |