Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL602792 | 0.92 | GPBAR1 (0.79) | GPBAR1 | |
| SCHEMBL602115 | 0.92 | GPBAR1 (0.79) | GPBAR1 | |
| SCHEMBL601244 | 0.91 | GPBAR1 (0.80) | GPBAR1 | |
| SCHEMBL603934 | 0.90 | GPBAR1 (0.79) | GPBAR1 | |
| SCHEMBL604953 | 0.90 | GPBAR1 (0.79) | GPBAR1 | |
| SCHEMBL10227756 | 0.89 | GPBAR1 (0.78) | GPBAR1 | |
| SCHEMBL603838 | 0.88 | GPBAR1 (0.76) | GPBAR1 | |
| SCHEMBL604454 | 0.88 | GPBAR1 (0.74) | GPBAR1 | |
| SCHEMBL601313 | 0.88 | GPBAR1 (0.90) | GPBAR1 | |
| SCHEMBL601987 | 0.88 | GPBAR1 (0.76) | GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093845-A1 | TRIAZOLE AND IMIDAZOLE DERIVATIVES FOR USE AS TGR5 AGONISTS IN THE TREATMENT OF DIABETES AND OBESITY | EXELIXIS, INC. (US) | 2010-08-19 | — | — | WO | disclosed |