SCHEMBL13263138

SCHEMBL13263138

CCCCCCCC1CCC(C2CCC(c3ccc(-c4ccc(-c5ccc(C6CO6)c(F)c5F)cc4)c(F)c3)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
CYP3A4 P08684 2/20 0.32
CYP2C9 P11712 1/20 0.32
FASN P49327 1/20 0.32
RARB P10826 1/20 0.31
CYP2C8 P10632 1/20 0.30
S1PR3 Q99500 1/20 0.30
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13000722 0.97 GAA (0.35) GAAMAPTCYP3A4CYP2C9FASN
SCHEMBL10163658 0.92 CYP2C9 (0.34) MAPTCYP3A4CYP2C9FASNAPP
SCHEMBL10152260 0.89 CYP2C9 (0.36) MAPTCYP3A4CYP2C9FASNAPP
SCHEMBL2606304 0.86 CYP2C9 (0.36) GAAMAPTCYP3A4CYP2C9
SCHEMBL10043249 0.86 CYP3A4 (0.41) GAAMAPTCYP3A4CYP2C9FASN
SCHEMBL10043215 0.86 CYP3A4 (0.41) GAAMAPTCYP3A4CYP2C9FASN
SCHEMBL10043220 0.85 CYP3A4 (0.41) GAAMAPTCYP3A4CYP2C9FASN
SCHEMBL10043246 0.85 CYP3A4 (0.41) GAAMAPTCYP3A4CYP2C9FASN
SCHEMBL9019527 0.85 CYP3A4 (0.31) CYP3A4CYP2C9
SCHEMBL8958989 0.85 CYP3A4 (0.36) GAAMAPTCYP3A4CYP2C9FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2206695-A1 TETRA- OR PENTA-CYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT Chisso Corporation (JP) 2010-07-14 EP disclosed