Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 10/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13264188 | 0.89 | GCK (0.60) | GCK | |
| SCHEMBL13264184 | 0.88 | GCK (0.42) | GCKPTGS2 | |
| SCHEMBL421483 | 0.86 | GCK (0.48) | GCK | |
| SCHEMBL13264120 | 0.86 | GCK (0.49) | GCK | |
| SCHEMBL420640 | 0.85 | GCK (0.48) | GCK | |
| SCHEMBL13264303 | 0.84 | GCK (0.48) | GCK | |
| SCHEMBL13264304 | 0.83 | GCK (0.47) | GCK | |
| SCHEMBL425176 | 0.81 | GCK (0.47) | GCK | |
| SCHEMBL425663 | 0.74 | GCK (0.41) | GCK | |
| SCHEMBL428385 | 0.74 | GCK (0.43) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010082601-A1 | NOVEL 2,5-DISUBSTITUTED PYRROLE DERIVATIVE | 第一三共株式会社 (JP) | 2010-07-22 | — | — | WO | disclosed |