SCHEMBL13264196

SCHEMBL13264196

C[C@@H](CF)Oc1cc(Oc2cnc(S(C)(=O)=O)cn2)cc(-c2ccc(C3=NC(CO)CO3)[nH]2)c1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCK P35557 9/20 0.36
GPR119 Q8TDV5 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13264131 0.92 GCK (0.39) GCK
SCHEMBL13264292 0.90 GCK (0.36) GCK
SCHEMBL422911 0.89 GCK (0.38) GCK
SCHEMBL422624 0.87 GCK (0.38) GCKGPR119
SCHEMBL13264293 0.85 GCK (0.39) GCK
SCHEMBL1057149 0.85 GCK (0.40) GCK
SCHEMBL1057457 0.85 GCK (0.40) GCK
SCHEMBL13264306 0.84 GCK (0.35) GCK
SCHEMBL13264132 0.84 GCK (0.35) GCK
SCHEMBL1056440 0.84 GCK (0.37) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010082601-A1 NOVEL 2,5-DISUBSTITUTED PYRROLE DERIVATIVE 第一三共株式会社 (JP) 2010-07-22 WO disclosed