Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745211 | 1.00 | CYP4F2 (0.36) | CYP4F2CYP4A11POLBALDH1A1GAA | |
| SCHEMBL6744520 | 0.92 | CYP4F2 (0.36) | CYP4F2CYP4A11POLBALDH1A1GAA | |
| SCHEMBL6744908 | 0.92 | CYP4F2 (0.37) | CYP4F2CYP4A11ALDH1A1GAATSHR | |
| SCHEMBL2476417 | 0.87 | CYP4F2 (0.38) | CYP4F2CYP4A11ALDH1A1GAATSHR | |
| SCHEMBL2476415 | 0.87 | CYP4F2 (0.38) | CYP4F2CYP4A11ALDH1A1GAATSHR | |
| SCHEMBL6745521 | 0.84 | CYP4F2 (0.37) | CYP4F2CYP4A11ALDH1A1GAAFFAR1 | |
| SCHEMBL10151162 | 0.84 | CYP4F2 (0.37) | CYP4F2CYP4A11ALDH1A1GAAFFAR1 | |
| SCHEMBL10164961 | 0.83 | CYP4F2 (0.39) | CYP4F2CYP4A11POLBALDH1A1GAA | |
| SCHEMBL10134599 | 0.82 | CYP4F2 (0.38) | CYP4F2CYP4A11ALDH1A1GAAMGLL | |
| SCHEMBL6799092 | 0.81 | CYP4F2 (0.38) | CYP4F2CYP4A11ALDH1A1GAAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074088-A1 | CYCLIC AMINE COMPOUNDS | 第一三共株式会社 (JP) | 2010-07-01 | — | — | WO | disclosed |