Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.72 |
| ▸ | ALDH1A3 | P47895 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2064778 | 0.88 | NR4A2 (0.83) | NR4A2ALDH1A3ALDH1A1ALDH1A2CYP2C9 | |
| SCHEMBL2064405 | 0.86 | NR4A2 (0.72) | NR4A2ALDH1A3ALDH1A1ALDH1A2CYP2C9 | |
| SCHEMBL2064019 | 0.85 | NR4A2 (0.81) | NR4A2ALDH1A3ALDH1A1ALDH1A2CYP2C9 | |
| SCHEMBL2064292 | 0.84 | NR4A2 (1.00) | NR4A2ALDH1A3ALDH1A1ALDH1A2CYP2C9 | |
| SCHEMBL1474679 | 0.79 | NR4A2 (0.66) | NR4A2ALDH1A3ALDH1A1ALDH1A2CYP2C9 | |
| SCHEMBL2064759 | 0.78 | NR4A2 (0.67) | NR4A2ALDH1A3ALDH1A1CYP2C9KCNH2 | |
| SCHEMBL3431887 | 0.76 | NR4A2 (0.62) | NR4A2ALDH1A3CYP2C9KCNH2PDCD1 | |
| SCHEMBL2064866 | 0.75 | NR4A2 (0.58) | NR4A2ALDH1A3ALDH1A1ALDH1A2CYP2C9 | |
| SCHEMBL2064734 | 0.74 | NR4A2 (0.73) | NR4A2ALDH1A3ALDH1A1ALDH1A2CYP2C9 | |
| SCHEMBL3429968 | 0.74 | NR4A2 (0.49) | NR4A2ALDH1A3ALDH1A1ALDH1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262803-B1 | POLYSUBSTITUTED DERIVATIVES OF 2-ARYL-6-PHENYL-IMIDAZO[L,2-A] PYRIDINES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2012-10-17 | — | — | EP | claimed |
| EP-2262803-B1 | POLYSUBSTITUTED DERIVATIVES OF 2-ARYL-6-PHENYL-IMIDAZO[L,2-A] PYRIDINES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2012-10-17 | — | — | EP | disclosed |