Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 2/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12716627 | 0.86 | S1PR5 (0.58) | SCN4AABL1RIN1S1PR5KDM4E | |
| SCHEMBL26332190 | 0.85 | MEN1 (0.58) | SCN4AABL1RIN1S1PR5KDM4E | |
| SCHEMBL20250776 | 0.82 | ABL1 (0.63) | SCN4AABL1RIN1S1PR5KDM4E | |
| SCHEMBL19578326 | 0.82 | ABL1 (0.63) | SCN4AABL1RIN1S1PR5KDM4E | |
| SCHEMBL8601138 | 0.79 | S1PR5 (0.61) | SCN4AABL1RIN1S1PR5KDM4E | |
| SCHEMBL5567542 | 0.79 | SCN4A (0.62) | SCN4AABL1RIN1S1PR5KDM4E | |
| SCHEMBL12174911 | 0.79 | SCN4A (0.62) | SCN4AABL1RIN1S1PR5KDM4E | |
| SCHEMBL12174984 | 0.79 | SCN4A (0.62) | SCN4AABL1RIN1S1PR5KDM4E | |
| SCHEMBL16301219 | 0.78 | S1PR5 (0.77) | SCN4AS1PR5KDM4EALDH1A1S1PR4 | |
| SCHEMBL250506 | 0.78 | S1PR5 (0.77) | SCN4AS1PR5KDM4EALDH1A1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-A1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2010-07-14 | — | — | EP | disclosed |