Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 11/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1327727 | 0.88 | C5AR1 (0.42) | C5AR1OPRK1ALDH1A1 | |
| SCHEMBL1327626 | 0.87 | C5AR1 (0.41) | C5AR1OPRK1ALDH1A1CD274 | |
| SCHEMBL1327969 | 0.86 | C5AR1 (0.41) | C5AR1ALDH1A1CD274 | |
| SCHEMBL1328912 | 0.86 | C5AR1 (0.40) | C5AR1OPRK1ALDH1A1CD274 | |
| SCHEMBL1327366 | 0.83 | C5AR1 (0.42) | C5AR1POLBGAA | |
| SCHEMBL1328344 | 0.82 | C5AR1 (0.41) | C5AR1GAA | |
| SCHEMBL1328062 | 0.81 | KDM4E (0.52) | C5AR1POLBALDH1A1CD274SMN1; SMN2 | |
| SCHEMBL1328948 | 0.81 | C5AR1 (0.42) | C5AR1POLBALDH1A1CD274GAA | |
| SCHEMBL2139080 | 0.80 | MEN1 (0.43) | C5AR1POLBALDH1A1CD274GAA | |
| SCHEMBL2140205 | 0.80 | MEN1 (0.43) | C5AR1POLBALDH1A1CD274GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110281837-A1 | 3-SUBSTITUTED-6-ARYL PYRIDINES | HUTCHINSON ALAN J (US) | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110281837-A1 | 3-SUBSTITUTED-6-ARYL PYRIDINES | C3AR1, C5AR1, C5AR2 | C5AR1 2/4885OPRK1 475/4885S1PR1 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.