Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13282542 | 0.87 | — | — | |
| SCHEMBL13282541 | 0.86 | GRM5 (0.48) | GRM5 | |
| SCHEMBL2482584 | 0.84 | PDE10A (0.48) | PDE10A | |
| SCHEMBL13282545 | 0.77 | SCN9A (0.47) | — | |
| SCHEMBL13282736 | 0.76 | — | — | |
| SCHEMBL13282540 | 0.76 | — | — | |
| SCHEMBL2485128 | 0.73 | CSNK1A1 (0.47) | PDE10A | |
| SCHEMBL2488254 | 0.71 | CSNK1A1 (0.50) | PDE10A | |
| SCHEMBL2491583 | 0.71 | PDE10A (0.71) | PDE10A | |
| SCHEMBL27930256 | 0.71 | NR4A1 (0.49) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077992-A1 | AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS | AMGEN INC. (US) | 2010-07-08 | — | — | WO | disclosed |