SCHEMBL1328440

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1327456	0.90	CACNA1I (0.51)	POLBSMN1; SMN2ALDH1A1NPC1RAB9A
	SCHEMBL27936786	0.85	EPHX2 (0.55)	SMN1; SMN2ALDH1A1NPC1RAB9ALMNA
	SCHEMBL1328289	0.85	SMYD3 (0.57)	POLBSMN1; SMN2ALDH1A1NPC1RAB9A
	SCHEMBL1328568	0.81	CHRM4 (0.42)	ITGB3ITGA2B
	SCHEMBL1327297	0.80	TMEM97 (0.47)	—
	SCHEMBL1327546	0.80	CHRM4 (0.53)	SMN1; SMN2ALDH1A1NPC1RAB9AOPRD1
	SCHEMBL1328281	0.80	TMEM97 (0.48)	POLBITGB3ITGA2BCACNA1I
	SCHEMBL1328189	0.80	CHRM4 (0.42)	ITGB3ITGA2B
	SCHEMBL1326618	0.80	MEN1 (0.56)	POLBALDH1A1NPC1RAB9A
	SCHEMBL2307391	0.80	TMEM97 (0.48)	POLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.