Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.59 |
| ▸ | CNR1 | P21554 | 8/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9891980 | 0.86 | CNR2 (0.56) | CNR2CNR1PIK3CDPIK3CAPIK3CG | |
| SCHEMBL9891997 | 0.86 | CNR2 (0.56) | CNR2CNR1PIK3CDPIK3CAPIK3CG | |
| SCHEMBL9891999 | 0.82 | CNR2 (0.62) | CNR2CNR1 | |
| SCHEMBL9891984 | 0.82 | CNR2 (0.62) | CNR2CNR1 | |
| SCHEMBL9892000 | 0.81 | CNR2 (0.69) | CNR2CNR1GCK | |
| SCHEMBL9891985 | 0.81 | CNR2 (0.69) | CNR2CNR1GCK | |
| SCHEMBL9891990 | 0.77 | CNR2 (0.52) | CNR2GCK | |
| SCHEMBL9892003 | 0.77 | CNR2 (0.52) | CNR2GCK | |
| SCHEMBL2576705 | 0.75 | CNR2 (0.74) | CNR2CNR1 | |
| SCHEMBL9892042 | 0.74 | CNR2 (1.00) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077836-A2 | PYRROLIDINE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-07-08 | — | — | WO | disclosed |