Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.46 |
| ▸ | FAP | Q12884 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12257899 | 0.83 | DPP4 (0.47) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL8265865 | 0.83 | DPP4 (0.47) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL17832776 | 0.83 | DPP4 (0.47) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL25067818 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAATMKMT2AALDH1A1 | |
| Carbamic Acid SCHEMBL27983182 | 0.78 | SLC7A5 (0.44) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL22208015 | 0.75 | ATM (0.46) | SMN1; SMN2LMNAATMKMT2AALDH1A1 | |
| SCHEMBL22197286 | 0.74 | DPP4 (0.48) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL21356918 | 0.73 | DPP4 (0.50) | DPP8DPP7DPP4DPP9FAP | |
| SCHEMBL417121 | 0.72 | SMN1; SMN2 (0.40) | DPP4SMN1; SMN2LMNAATMKMT2A | |
| SCHEMBL10100337 | 0.72 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAATMKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010085128-A2 | PROCESSES FOR PREPARING HIV REVERSE TRANSCRIPTASE INHIBITORS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-07-29 | — | — | WO | disclosed |