Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.57 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722114 | 0.87 | MDM4 (0.63) | MDM4TP53MDM2CASP3 | |
| SCHEMBL3722116 | 0.87 | MDM4 (0.63) | MDM4TP53MDM2CASP3 | |
| SCHEMBL13284069 | 0.87 | MDM4 (0.62) | MDM4TP53MDM2CASP3TLR2 | |
| SCHEMBL13284070 | 0.85 | MDM4 (0.64) | MDM4TP53MDM2CASP3 | |
| SCHEMBL3779667 | 0.85 | MDM4 (0.64) | MDM4TP53MDM2CASP3 | |
| SCHEMBL31370349 | 0.85 | MDM4 (0.68) | MDM4TP53MDM2CASP3 | |
| SCHEMBL3728174 | 0.84 | MDM4 (0.56) | MDM4TP53MDM2CASP3TLR2 | |
| SCHEMBL29615199 | 0.84 | MDM4 (0.56) | MDM4TP53MDM2CASP3TLR2 | |
| SCHEMBL3728179 | 0.84 | MDM4 (0.56) | MDM4TP53MDM2CASP3TLR2 | |
| SCHEMBL13284068 | 0.83 | MDM2 (0.62) | MDM4TP53MDM2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210882-A1 | Synthesis of new protected azahistidine, their processes and their use in synthesises | Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) | 2010-07-28 | — | — | EP | disclosed |