SCHEMBL13286451

SCHEMBL13286451

N#Cc1nc2nc3c4cc5c(cc4c(=O)n3c2nc1C#N)c(=O)n1c2nc(C#N)c(C#N)nc2nc51

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPT P10636 1/20 0.35
USP8 P40818 5/20 0.33
USP7 Q93009 3/20 0.33
USP47 Q96K76 1/20 0.33
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13286450 1.00 MEN1 (0.35) MEN1KMT2AMAPTUSP8USP7
SCHEMBL13260711 0.88 MEN1 (0.30) MEN1KMT2AMAPT
SCHEMBL13260781 0.88 MEN1 (0.30) MEN1KMT2AMAPT
SCHEMBL13286479 0.84 USP8 (0.34) MEN1KMT2AMAPTUSP8USP7
SCHEMBL13286478 0.84 USP8 (0.34) MEN1KMT2AMAPTUSP8USP7
SCHEMBL13260728 0.80
SCHEMBL13286445 0.80 KDM4E (0.41) MEN1KMT2AMAPTUSP8USP7
SCHEMBL13286449 0.80 KDM4E (0.41) MEN1KMT2AMAPTUSP8USP7
SCHEMBL13286471 0.79
SCHEMBL13260825 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130161591-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2013-06-27 US disclosed
US-8372527-B2 Material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2013-02-12 US disclosed
US-20100187519-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2010-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100187519-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT L1CAM, ETV6, ELAVL1 MEN1 1579/4885KMT2A 1593/4885MAPT 1786/4885
US-20130161591-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT L1CAM, ETV6, ELAVL1 MEN1 1579/4885KMT2A 1593/4885MAPT 1786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.