Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 7/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1327187 | 0.85 | C5AR1 (0.35) | C5AR1ALOX5APFEN1 | |
| SCHEMBL2141456 | 0.81 | C5AR1 (0.33) | C5AR1 | |
| SCHEMBL1327746 | 0.76 | C5AR1 (0.31) | C5AR1 | |
| SCHEMBL1327286 | 0.75 | DHODH (0.38) | — | |
| SCHEMBL1328707 | 0.72 | NPSR1 (0.38) | C5AR1ALOX5APFEN1 | |
| SCHEMBL1327704 | 0.72 | C5AR1 (0.38) | C5AR1ALOX5APFEN1 | |
| SCHEMBL1762776 | 0.72 | C5AR1 (0.31) | C5AR1 | |
| SCHEMBL1326960 | 0.71 | C5AR1 (0.38) | C5AR1 | |
| SCHEMBL1327582 | 0.70 | NPSR1 (0.36) | C5AR1 | |
| SCHEMBL1328717 | 0.70 | C5AR1 (0.37) | C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110281837-A1 | 3-SUBSTITUTED-6-ARYL PYRIDINES | HUTCHINSON ALAN J (US) | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110281837-A1 | 3-SUBSTITUTED-6-ARYL PYRIDINES | C3AR1, C5AR1, C5AR2 | C5AR1 2/4885ALOX5AP 568/4885FEN1 4331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.