SCHEMBL13286809

SCHEMBL13286809

CC1=C(O)C(C)C(=O)C1=O

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.34
KDM4E B2RXH2 1/20 0.34
TP53 P04637 1/20 0.34
MAPK1 P28482 1/20 0.34
CYP2C19 P33261 1/20 0.34
HSD17B10 Q99714 1/20 0.34
DUSP3 P51452 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13286825 0.83
SCHEMBL17149307 0.69
SCHEMBL18677022 0.67 MAPT (0.33) MAPTKDM4ETP53MAPK1CYP2C19
SCHEMBL18942041 0.65
SCHEMBL13906871 0.64 MAPT (0.32) MAPTKDM4ETP53MAPK1CYP2C19
SCHEMBL9403423 0.62
SCHEMBL17617769 0.62 DUSP3 (0.42) MAPTKDM4ETP53MAPK1CYP2C19
SCHEMBL10351240 0.61
SCHEMBL14953628 0.59
SCHEMBL13228008 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8383830-B2 Cyanine compounds and their use in staining biological samples SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD (CN) 2013-02-26 US disclosed
US-8383830-B2 Cyanine compounds and their use in staining biological samples SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD (CN) 2013-02-26 US disclosed
US-8334109-B2 Reagent for blood analysis and method of using the same SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) 2012-12-18 US disclosed
US-8334109-B2 Reagent for blood analysis and method of using the same SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) 2012-12-18 US disclosed
US-20100143955-A1 REAGENT FOR BLOOD ANALYSIS AND METHOD OF USING THE SAME SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) 2010-06-10 US disclosed
US-20100143955-A1 REAGENT FOR BLOOD ANALYSIS AND METHOD OF USING THE SAME SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) 2010-06-10 US disclosed
US-20100112584-A1 CYANINE COMPOUNDS AND THEIR USE IN STAINING BIOLOGICAL SAMPLES SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) 2010-05-06 US disclosed
US-20100112584-A1 CYANINE COMPOUNDS AND THEIR USE IN STAINING BIOLOGICAL SAMPLES SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (CN) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100112584-A1 CYANINE COMPOUNDS AND THEIR USE IN STAINING BIOLOGICAL SAMPLES XPA, HNRNPA2B1, IK MAPT 3959/4885KDM4E 2229/4885TP53 464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.