SCHEMBL13287906

SCHEMBL13287906

Cc1cc(N)cc(C(=O)NC(C)C)c1NC(=O)C1CC(Cl)=NN1c1ncccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 13/20 0.40
PPARD Q03181 1/20 0.33
GRM4 Q14833 1/20 0.33
ALOX5 P09917 1/20 0.32
P2RX7 Q99572 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9289054 0.93 MALT1 (0.39) MALT1PPARDGRM4
SCHEMBL9289365 0.92 MALT1 (0.42) MALT1PPARD
SCHEMBL12575514 0.91 MALT1 (0.41) MALT1PPARDGRM4P2RX7
SCHEMBL9289049 0.90 MALT1 (0.40) MALT1GRM4
SCHEMBL13356326 0.90 MALT1 (0.40) MALT1GRM4
SCHEMBL13003161 0.90 MALT1 (0.37) MALT1PPARDP2RX7
SCHEMBL9289366 0.89 MALT1 (0.39) MALT1
SCHEMBL9286849 0.86 MALT1 (0.38) MALT1
SCHEMBL11888080 0.86 MALT1 (0.41) MALT1GRM4
SCHEMBL12438369 0.84 MALT1 (0.40) MALT1GRM4P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010063670-A1 SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2010-06-10 WO disclosed
WO-2009010260-A2 CONDENSED ANTHRANILAMIDE INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2009-01-22 WO disclosed