Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR2 | P30874 | 5/20 | 0.50 |
| ▸ | SSTR1 | P30872 | 4/20 | 0.50 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.50 |
| ▸ | SSTR3 | P32745 | 4/20 | 0.50 |
| ▸ | SSTR5 | P35346 | 4/20 | 0.50 |
| ▸ | PLAU | P00749 | 2/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | CTSG | P08311 | 2/20 | 0.48 |
| ▸ | IL23R | Q5VWK5 | 4/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | BAD | Q92934 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13113566 | 0.99 | SSTR2 (0.50) | SSTR2SSTR1SSTR4SSTR3SSTR5 | |
| SCHEMBL12082795 | 0.95 | IL23R (0.52) | SSTR2SSTR1SSTR4SSTR3SSTR5 | |
| SCHEMBL13113585 | 0.88 | PLAU (0.51) | SSTR2SSTR1SSTR4SSTR3SSTR5 | |
| SCHEMBL16349705 | 0.87 | SSTR2 (0.47) | SSTR2SSTR1SSTR4SSTR3SSTR5 | |
| SCHEMBL13287950 | 0.87 | ALB (0.46) | SSTR2SSTR1SSTR4SSTR3SSTR5 | |
| SCHEMBL13287918 | 0.86 | ALB (0.47) | SSTR2SSTR1SSTR4SSTR3SSTR5 | |
| SCHEMBL13287934 | 0.84 | IL23R (0.52) | IL23RBCL2L1BAD | |
| SCHEMBL13649552 | 0.84 | MDM2 (0.51) | PLAUAVPR1ACTSGKLK7TNFSF11 | |
| SCHEMBL16349623 | 0.84 | PLAU (0.46) | SSTR2SSTR1SSTR4SSTR3SSTR5 | |
| SCHEMBL13113570 | 0.81 | SSTR2 (0.44) | SSTR2SSTR1SSTR4SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737252-B2 | Peptide-based compounds | GE HEALTHCARE AS (NO) | 2010-06-15 | — | — | US | disclosed |