Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 14/20 | 0.65 |
| ▸ | CDK2 | P24941 | 6/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12954081 | 0.91 | GSK3B (0.65) | GSK3BCDK2CCNE1 | |
| SCHEMBL14412997 | 0.90 | GSK3B (0.68) | GSK3BCDK2CCNE1 | |
| SCHEMBL13288383 | 0.90 | GSK3B (0.67) | GSK3BCDK2CCNE1 | |
| SCHEMBL13119136 | 0.88 | GSK3B (0.65) | GSK3BCDK2CCNE1 | |
| SCHEMBL13121518 | 0.88 | GSK3B (0.65) | GSK3BCDK2CCNE1 | |
| SCHEMBL13121516 | 0.88 | GSK3B (0.69) | GSK3BCDK2CCNE1 | |
| SCHEMBL12952884 | 0.88 | GSK3B (0.73) | GSK3BCDK2CCNE1 | |
| SCHEMBL12954313 | 0.87 | GSK3B (0.68) | GSK3BCDK2CCNE1 | |
| SCHEMBL12954409 | 0.87 | GSK3B (0.67) | GSK3BCDK2CCNE1 | |
| SCHEMBL13119070 | 0.87 | GSK3B (0.67) | GSK3BCDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2194058-A1 | Pyrazolopyrimidines suitable for the treatment of cancer diseases | SCHERING CORPORATION (US) | 2010-06-09 | — | — | EP | disclosed |