Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.45 |
| ▸ | CDK2 | P24941 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | F13A1 | P00488 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13289466 | 0.95 | GSK3B (0.43) | GSK3BCDK2MEN1KMT2ACCR1 | |
| SCHEMBL14546009 | 0.92 | CDK2 (0.46) | GSK3BCDK2POLBALDH1A1FLT3 | |
| SCHEMBL13289547 | 0.91 | CDK2 (0.46) | GSK3BCDK2CCR1FLT3CCNA2 | |
| SCHEMBL13289373 | 0.91 | GSK3B (0.42) | GSK3BCDK2MEN1KMT2AFLT3 | |
| SCHEMBL13121203 | 0.90 | GSK3B (0.59) | GSK3BCDK2CCNA2CCNA1 | |
| SCHEMBL13289569 | 0.90 | CDK2 (0.51) | GSK3BCDK2CCNA2CCNA1 | |
| SCHEMBL13289272 | 0.88 | GSK3B (0.48) | GSK3BCDK2MEN1KMT2ALMNA | |
| SCHEMBL13289128 | 0.88 | CDK2 (0.44) | GSK3BCDK2CCR1POLBALDH1A1 | |
| SCHEMBL13288981 | 0.88 | CDK2 (0.46) | GSK3BCDK2CCR1ALDH1A1FLT3 | |
| SCHEMBL13289301 | 0.88 | CDK2 (0.46) | GSK3BCDK2MEN1KMT2ACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2194058-A1 | Pyrazolopyrimidines suitable for the treatment of cancer diseases | SCHERING CORPORATION (US) | 2010-06-09 | — | — | EP | disclosed |