Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.49 |
| ▸ | GSK3B | P49841 | 7/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.36 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.36 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13289141 | 0.95 | CDK2 (0.53) | CDK2GSK3BCCNA2CCNA1KCNN1 | |
| SCHEMBL12954253 | 0.90 | CDK2 (0.63) | CDK2GSK3BCCNA2CCNA1 | |
| SCHEMBL12954278 | 0.88 | CDK2 (0.52) | CDK2GSK3BCCNA2CCNA1RAB9A | |
| SCHEMBL13288974 | 0.88 | CDK2 (0.52) | CDK2GSK3BCCNA2CCNA1RAB9A | |
| SCHEMBL13289037 | 0.88 | CDK2 (0.44) | CDK2GSK3BRAB9ASMN1; SMN2 | |
| SCHEMBL13289375 | 0.87 | CDK2 (0.54) | CDK2GSK3BCCNA2CCNA1KCNN3 | |
| SCHEMBL14613377 | 0.86 | GSK3B (0.42) | CDK2GSK3BCCNA2CCNA1PKM | |
| SCHEMBL13289430 | 0.85 | GSK3B (0.49) | CDK2GSK3BCCNA2CCNA1KCNN3 | |
| SCHEMBL13289440 | 0.85 | CDK2 (0.51) | CDK2GSK3BCCNA2CCNA1PKM | |
| SCHEMBL13120659 | 0.85 | CDK2 (0.67) | CDK2GSK3BCCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2194058-A1 | Pyrazolopyrimidines suitable for the treatment of cancer diseases | SCHERING CORPORATION (US) | 2010-06-09 | — | — | EP | disclosed |