Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 14/20 | 0.59 |
| ▸ | CDK2 | P24941 | 6/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14545294 | 0.90 | GSK3B (0.64) | GSK3BCDK2CCNE1 | |
| SCHEMBL13289624 | 0.89 | GSK3B (0.55) | GSK3BCDK2CCNE1 | |
| SCHEMBL13122765 | 0.88 | GSK3B (0.77) | GSK3BCDK2CCNE1 | |
| SCHEMBL13289831 | 0.85 | GSK3B (0.52) | GSK3BCDK2CCNE1 | |
| SCHEMBL12954561 | 0.85 | GSK3B (0.59) | GSK3BCDK2CCNE1 | |
| SCHEMBL13305283 | 0.85 | GSK3B (0.56) | GSK3BCDK2CCNE1 | |
| SCHEMBL13289823 | 0.85 | GSK3B (0.56) | GSK3BCDK2CCNE1 | |
| SCHEMBL13289821 | 0.85 | CDK7 (0.56) | GSK3BCDK2CCNE1 | |
| SCHEMBL13290026 | 0.84 | GSK3B (0.53) | GSK3BCDK2CCNE1 | |
| SCHEMBL13289830 | 0.84 | CDK7 (0.56) | GSK3BCDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2194058-A1 | Pyrazolopyrimidines suitable for the treatment of cancer diseases | SCHERING CORPORATION (US) | 2010-06-09 | — | — | EP | disclosed |