SCHEMBL13291663

SCHEMBL13291663

Clc1cccc(/C=C/C=C/c2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.61
CHAT P28329 1/20 0.56
MAOA P21397 3/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2C9 P11712 1/20 0.55
RELA Q04206 1/20 0.55
CHRM5 P08912 1/20 0.52
FBP1 P09467 1/20 0.52
MAPK1 P28482 2/20 0.48
NPC1 O15118 1/20 0.48
POLB P06746 1/20 0.48
MAPT P10636 1/20 0.48
RECQL P46063 1/20 0.48
RAB9A P51151 1/20 0.48
GRIN1 Q05586 1/20 0.47
GRIN2B Q13224 1/20 0.47
EGFR P00533 1/20 0.47
MMP1 P03956 1/20 0.47
MMP2 P08253 1/20 0.47
MMP9 P14780 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11471054 0.93 CYP1A2 (0.61) MAOBCHATMAOACYP1A2CYP2C9
SCHEMBL29446280 0.91 CHAT (0.66) MAOBCHATMAOACYP1A2CYP2C9
SCHEMBL699874 0.91 CHAT (0.66) MAOBCHATMAOACYP1A2CYP2C9
SCHEMBL699875 0.91 CHAT (0.66) MAOBCHATMAOACYP1A2CYP2C9
SCHEMBL699365 0.84 CHAT (0.67) MAOBCHATMAOACYP1A2CYP2C9
SCHEMBL699364 0.84 CHAT (0.67) MAOBCHATMAOACYP1A2CYP2C9
SCHEMBL9156045 0.83 CYP1A2 (0.47) MAOBCHATMAOACYP1A2CYP2C9
SCHEMBL11844491 0.81 CYP1A2 (0.64) MAOBMAOACYP1A2CYP2C9FBP1
SCHEMBL11851984 0.81 CYP1A2 (0.64) MAOBMAOACYP1A2CYP2C9FBP1
SCHEMBL1307669 0.81 CCNB2 (0.60) MAOBCHATMAOACYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1860095-B1 Diphenylamine derivative, production method therefor and electrophotographic photoconductor KYOCERA MITA CORP (JP) 2013-03-20 EP disclosed
US-7745081-B2 Diphenyl amine derivative, production method therefor and electrophotographic photoconductor KYOCERA MITA CORPORATION (JP) 2010-06-29 US disclosed
US-7745081-B2 Diphenyl amine derivative, production method therefor and electrophotographic photoconductor KYOCERA MITA CORPORATION (JP) 2010-06-29 US disclosed
US-20070275314-A1 Diphenyl amine derivative, production method therefor and electrophotographic photoconductor KYOCERA MITA CORPORATION (JP) 2007-11-29 US disclosed
US-20070275314-A1 Diphenyl amine derivative, production method therefor and electrophotographic photoconductor KYOCERA MITA CORPORATION (JP) 2007-11-29 US disclosed
EP-1860095-A2 Diphenylamine derivative, production method therefor and electrophotographic photoconductor Kyocera Mita Corporation (JP) 2007-11-28 EP disclosed