SCHEMBL132930

SCHEMBL132930

Cc1ccc(OP(=O)(Oc2ccc(C)cc2C)N2CCN(P(=O)(Oc3ccc(C)cc3C)Oc3ccc(C)cc3C)CC2)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 5/20 0.42
▸ MEN1 O00255 4/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.42
▸ LMNA P02545 2/20 0.40
▸ KDM4E B2RXH2 3/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ HPGD P15428 5/20 0.38
▸ HTR1A P08908 2/20 0.38
▸ HTR3A P46098 2/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ GLA P06280 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ USP2 O75604 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ MAPK1 P28482 2/20 0.36
▸ TSHR P16473 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ CYP1A2 P05177 1/20 0.35
▸ CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL130226 0.79 MAPT (0.45) KMT2AMEN1SMN1; SMN2LMNAKDM4E
SCHEMBL108984 0.77 CYP3A4 (0.50) KMT2AMEN1SMN1; SMN2LMNAALDH1A1
SCHEMBL29349879 0.77 CYP3A4 (0.50) KMT2AMEN1SMN1; SMN2LMNAALDH1A1
SCHEMBL14229933 0.76 MEN1 (0.44) KMT2AMEN1SMN1; SMN2LMNAHPGD
SCHEMBL19348756 0.74 MEN1 (0.42) KMT2AMEN1SMN1; SMN2LMNAHPGD
SCHEMBL5667322 0.74 HPGD (0.42) KMT2AMEN1SMN1; SMN2LMNAHPGD
SCHEMBL130225 0.74 CYP3A4 (0.57) KMT2AMEN1LMNAALDH1A1GAA
SCHEMBL497308 0.74 HPGD (0.45) KMT2AMEN1SMN1; SMN2LMNAHPGD
SCHEMBL109597 0.74 INPPL1 (0.52) LMNAHPGDTDP1
SCHEMBL6862372 0.74 MEN1 (0.42) KMT2AMEN1SMN1; SMN2LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1452567-B1 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2012-03-07 — — EP disclosed
EP-1466946-B1 FLAME-RETARDANT RESIN COMPOSITION POLYPLASTICS CO (JP) 2011-11-09 — — EP disclosed
US-7411013-B2 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2008-08-12 — — US disclosed
US-7205346-B2 halogen-free, fireproof mixture of thermoplastic resins, containing phosphorus compounds, aromatic resins, nitrogen compounds, metal compounds, stabilizer agents and water repellants POLYPLASTICS CO., LTD. (JP) 2007-04-17 — — US disclosed
US-7115677-B2 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2006-10-03 — — US disclosed
US-20060074154-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2006-04-06 — — US disclosed
US-20040266916-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-12-30 — — US disclosed
US-20040254270-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-12-16 — — US disclosed
EP-1466946-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2004-10-13 — — EP disclosed
EP-1452567-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co Ltd (JP) 2004-09-01 — — EP disclosed
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