Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 17/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL643058 | 0.92 | CHRM2 (0.62) | CHRM2CHRM3SLC2A1 | |
| SCHEMBL644727 | 0.90 | CHRM2 (0.58) | CHRM2CHRM3SLC2A1 | |
| SCHEMBL643141 | 0.88 | CHRM2 (0.63) | CHRM2CHRM3SLC2A1 | |
| SCHEMBL2455843 | 0.87 | CHRM2 (0.61) | CHRM2CHRM3SLC2A1 | |
| SCHEMBL643643 | 0.85 | CHRM2 (0.59) | CHRM2CHRM3SLC2A1 | |
| SCHEMBL1304021 | 0.83 | CHRM2 (0.78) | CHRM2CHRM3SLC2A1 | |
| SCHEMBL3764432 | 0.83 | CHRM2 (0.56) | CHRM2CHRM3SLC2A1 | |
| SCHEMBL356695 | 0.82 | CHRM2 (0.72) | CHRM2CHRM3 | |
| SCHEMBL3128994 | 0.81 | CHRM2 (0.68) | CHRM2CHRM3SLC2A1 | |
| SCHEMBL643689 | 0.81 | CHRM2 (0.58) | CHRM2CHRM3SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728144-B2 | Biphenyl compounds useful as muscarinic receptor antagonists | THERAVANCE, INC (US) | 2010-06-01 | — | — | US | disclosed |
| US-7728144-B2 | Biphenyl compounds useful as muscarinic receptor antagonists | THERAVANCE, INC (US) | 2010-06-01 | — | — | US | disclosed |