Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.55 |
| ▸ | MDM4 | O15151 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.52 |
| ▸ | TACR2 | P21452 | 3/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.45 |
| ▸ | CDC25B | P30305 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5840884 | 0.89 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL13296075 | 0.89 | TP53 (0.57) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL16967451 | 0.89 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL15516519 | 0.89 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL15514084 | 0.89 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL24378386 | 0.89 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL5840927 | 0.89 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL13296082 | 0.89 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL15973108 | 0.88 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL15973107 | 0.88 | TP53 (0.55) | TP53MDM2MDM4HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737287-B2 | Anomeric derivatives of monosaccharides | ALCHEMIA LIMITED (AU) | 2010-06-15 | — | — | US | disclosed |