Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 10/20 | 0.84 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.77 |
| ▸ | SLC10A2 | Q12908 | 4/20 | 0.77 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.77 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.77 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.77 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.77 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.73 |
| ▸ | SLC10A1 | Q14973 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.70 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.70 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12137402 | 1.00 | GPBAR1 (0.84) | GPBAR1NR1H4SLC10A2ABCB11ENPP2 | |
| SCHEMBL18563183 | 1.00 | GPBAR1 (0.84) | GPBAR1NR1H4SLC10A2ABCB11ENPP2 | |
| SCHEMBL22627117 | 1.00 | GPBAR1 (0.84) | GPBAR1NR1H4SLC10A2ABCB11ENPP2 | |
| SCHEMBL23345508 | 0.95 | GPBAR1 (0.82) | GPBAR1NR1H4SLC10A2ABCB11ENPP2 | |
| SCHEMBL22626961 | 0.95 | GPBAR1 (0.82) | GPBAR1NR1H4SLC10A2ABCB11ENPP2 | |
| SCHEMBL22627109 | 0.93 | GPBAR1 (0.80) | GPBAR1NR1H4SLC10A2ABCB11ENPP2 | |
| SCHEMBL23345531 | 0.93 | GPBAR1 (0.80) | GPBAR1NR1H4SLC10A2ABCB11ENPP2 | |
| SCHEMBL13851605 | 0.92 | GPBAR1 (0.78) | GPBAR1NR1H4SLC10A2ABCB11ENPP2 | |
| SCHEMBL12137424 | 0.92 | GPBAR1 (0.71) | GPBAR1NR1H4SLC10A2ABCB11ENPP2 | |
| SCHEMBL26714790 | 0.92 | GPBAR1 (0.83) | GPBAR1NR1H4SLC10A2ABCB11ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010062369-A2 | METHODS AND COMPOSITIONS FOR INHIBITING CLOSTRIDIUM DIFFICILE SPORE GERMINATION AND OUTGROWTH | TUFTS UNIVERSITY (US) | 2010-06-03 | — | — | WO | disclosed |