⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694784 | 0.92 | — | — | |
| SCHEMBL8318028 | 0.89 | EPHX1 (0.61) | — | |
| SCHEMBL8694717 | 0.89 | EPHX1 (0.61) | — | |
| SCHEMBL102619 | 0.89 | EPHX1 (0.61) | — | |
| SCHEMBL8939098 | 0.89 | EPHX1 (0.61) | — | |
| SCHEMBL6945997 | 0.89 | EPHX1 (0.61) | — | |
| SCHEMBL8939176 | 0.89 | EPHX1 (0.61) | — | |
| SCHEMBL8939134 | 0.89 | EPHX1 (0.61) | — | |
| SCHEMBL7899856 | 0.89 | EPHX1 (0.61) | — | |
| SCHEMBL217777 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3708539-A1 | DRY METHOD TO OBTAIN COATED CRYSTALLINE SILICA WITH REDUCED TOXICITY | Universitat Jaume I De Castellón (ES) | 2020-09-16 | — | — | EP | claimed |
| US-9944597-B2 | Polysubstituted pyrroles having microtubule-disrupting, cytotoxic and antitumor activities and methods of use thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-04-17 | — | — | US | claimed |
| US-20160297757-A1 | POLYSUBSTITUTED PYRROLES HAVING MICROTUBULE-DISRUPTING, CYTOTOXIC AND ANTITUMOR ACTIVITIES AND METHODS OF USE THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SY STEM (US) | 2016-10-13 | — | — | US | claimed |
| EP-2922893-B1 | MOISTURE-CURING COMPOSITIONS, PROCESSES FOR PRODUCING SAME AND USE OF SAME | EVONIK DEGUSSA GMBH (DE) | 2016-04-06 | — | — | EP | claimed |
| US-20150284609-A1 | MOISTURE-CURING COMPOSITIONS, PROCESS FOR PRODUCTION THEREOF AND USE THEREOF | EVONIK INDUSTRIES AG (DE) | 2015-10-08 | — | — | US | claimed |
| WO-2015039073-A1 | POLYSUBSTITUTED PYRROLES HAVING MICROTUBULE-DISRUPTING, CYTOTOXIC AND ANTITUMOR ACTIVITIES AND METHDS OF USE THEREOF | KELLOGG GLEN E (US) | 2015-03-19 | — | — | WO | claimed |
| EP-2646002-A2 | HYDROGEL MICROCAPSULES | Isp Investments Inc. (US) | 2013-10-09 | — | — | EP | claimed |
| EP-2555747-A2 | A COMBINATION OF CROSSLINKED CATIONIC POLYMER AND AMPHOLYTIC POLYMER FOR PERSONAL AND HOUSEHOLD APPLICATIONS | Lubrizol Advanced Materials, Inc. (US) | 2013-02-13 | — | — | EP | claimed |
| WO-2012075293-A2 | HYDROGEL MICROCAPSULES | ISP INVESTMENTS INC. (US) | 2012-06-07 | — | — | WO | claimed |
| EP-1304345-B1 | Aminoalkylalkoxysiloxan containing mixtures , their preparation process and their use | DEGUSSA (DE) | 2005-12-14 | — | — | EP | claimed |
| US-6770327-B2 | Aminoalkylalkoxysiloxane mixtures | DEGUSSA AG (DE) | 2004-08-03 | — | — | US | claimed |
| EP-0997469-B1 | Aminopropyl-functional siloxane oligomers | DEGUSSA (DE) | 2004-07-14 | — | — | EP | claimed |
| US-20030072873-A1 | Aminoalkylalkoxysiloxane mixtures | DEGUSSA AG (DE) | 2003-04-17 | — | — | US | claimed |
| US-6395858-B1 | AMINOALKYLSILANOL AND SIMILAR COMPOUNDS | DEGUSSA AG (DE) | 2002-05-28 | — | — | US | claimed |
| CN-113242897-B | Adhesive agent | 美国陶氏有机硅公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2024106213-A1 | METHOD FOR PRODUCING DISILOXANE COMPOUND | 信越化学工業株式会社 | 2024-05-23 | — | — | WO | disclosed |
| WO-2024096117-A1 | CARBON DIOXIDE ABSORBING LIQUID, AND CARBON DIOXIDE SEPARATION/RECOVERY METHOD | ａｒｔｉｅｎｃｅ株式会社 | 2024-05-10 | — | — | WO | disclosed |
| US-4472304-A | CARCINOSTATIC | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008711-B1 | A METHOD OF PREPARING A 2-HYDROXY-3-ISOPROPYL OR A 2-HYDROXY-3-TERT-BUTYLAMINOPROPYL AROMATIC ETHER | SMITHKLINE BECKMAN CORPORATION (US) | 1981-11-04 | — | — | EP | disclosed |
| EP-0008711-A1 | A method of preparing a 2-hydroxy-3-isopropyl or a 2-hydroxy-3-tert-butylaminopropyl aromatic ether | SMITHKLINE BECKMAN CORPORATION (US) | 1980-03-19 | — | — | EP | disclosed |