Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.82 |
| ▸ | GAA | P10253 | 4/20 | 0.82 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6285372 | 0.90 | KDM4E (1.00) | KDM4EGAAMAPTALDH1A1MEN1 | |
| SCHEMBL30854920 | 0.81 | KDM4E (1.00) | KDM4EGAAMAPTALDH1A1MEN1 | |
| SCHEMBL6102581 | 0.81 | KDM4E (1.00) | KDM4EGAAMAPTALDH1A1MEN1 | |
| SCHEMBL2003333 | 0.80 | KDM4E (0.75) | KDM4EGAAMAPTALDH1A1MEN1 | |
| SCHEMBL3408821 | 0.78 | KDM4E (0.73) | KDM4EGAAMAPTALDH1A1MEN1 | |
| SCHEMBL1757962 | 0.78 | KDM4E (0.73) | KDM4EGAAMAPTALDH1A1MEN1 | |
| SCHEMBL13401405 | 0.78 | KDM4E (0.73) | KDM4EGAAMAPTALDH1A1MEN1 | |
| SCHEMBL11338372 | 0.78 | KDM4E (0.73) | KDM4EGAAMAPTALDH1A1MEN1 | |
| SCHEMBL14389440 | 0.77 | KDM4E (0.71) | KDM4EGAAMAPTALDH1A1MEN1 | |
| SCHEMBL4204905 | 0.76 | KDM4E (0.69) | KDM4EGAAMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010062221-A1 | SUBSTITUTED 2-(5-HYDROXY-2-METHYL-1N-INDOLE-3-IL) ACETIC ACIDS AND ETHERS THEREOF AND THE USE OF SAME TO TREAT VIRAL DISEASES | АЛЛА XEM, ЛЛС (US) | 2010-06-03 | — | — | WO | disclosed |