Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LYN | P07948 | 16/20 | 0.47 |
| ▸ | LCK | P06239 | 15/20 | 0.47 |
| ▸ | SRC | P12931 | 15/20 | 0.47 |
| ▸ | KDR | P35968 | 15/20 | 0.47 |
| ▸ | INSR | P06213 | 13/20 | 0.47 |
| ▸ | HCK | P08631 | 13/20 | 0.47 |
| ▸ | CSF1R | P07333 | 4/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13269782 | 0.92 | LYN (0.56) | LYNLCKSRCKDRINSR | |
| SCHEMBL1825857 | 0.92 | KDR (0.48) | LYNLCKSRCKDRINSR | |
| SCHEMBL3240423 | 0.92 | LYN (0.47) | LYNLCKSRCKDRINSR | |
| SCHEMBL3238130 | 0.90 | LYN (0.49) | LYNLCKSRCKDRINSR | |
| SCHEMBL13302010 | 0.86 | CSF1R (0.51) | LYNLCKSRCKDRINSR | |
| SCHEMBL1824965 | 0.82 | LYN (0.58) | LYNLCKSRCKDRINSR | |
| SCHEMBL1827464 | 0.81 | LCK (0.69) | LYNLCKSRCKDRINSR | |
| SCHEMBL3232981 | 0.81 | LYN (0.54) | LYNLCKSRCKDRINSR | |
| SCHEMBL13467360 | 0.80 | LYN (0.54) | LYNLCKSRCKDRINSR | |
| SCHEMBL1828074 | 0.80 | LYN (0.59) | LYNLCKSRCKDRINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745437-B2 | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2010-06-29 | — | — | US | disclosed |