Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 18/20 | 0.49 |
| ▸ | LYN | P07948 | 18/20 | 0.49 |
| ▸ | SRC | P12931 | 18/20 | 0.49 |
| ▸ | KDR | P35968 | 18/20 | 0.49 |
| ▸ | INSR | P06213 | 16/20 | 0.49 |
| ▸ | HCK | P08631 | 15/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1826564 | 0.90 | LCK (0.60) | LCKLYNSRCKDRINSR | |
| SCHEMBL13301979 | 0.86 | LCK (0.54) | LCKLYNSRCKDRINSR | |
| SCHEMBL13301928 | 0.85 | LCK (0.47) | LCKLYNSRCKDRINSR | |
| SCHEMBL13301801 | 0.85 | MAPK14 (0.59) | LCKLYNSRCKDRINSR | |
| SCHEMBL13301821 | 0.84 | LCK (0.45) | LCKLYNSRCKDRINSR | |
| SCHEMBL13301782 | 0.82 | LCK (0.47) | LCKLYNSRCKDRINSR | |
| SCHEMBL13301994 | 0.81 | HCK (0.44) | LCKLYNSRCKDRINSR | |
| SCHEMBL13302019 | 0.81 | LCK (0.45) | LCKLYNSRCKDRINSR | |
| SCHEMBL13302020 | 0.81 | LCK (0.45) | LCKLYNSRCKDRINSR | |
| SCHEMBL13301984 | 0.81 | LCK (0.55) | LCKLYNSRCKDRINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745437-B2 | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2010-06-29 | — | — | US | disclosed |