Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 16/20 | 0.70 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.70 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.70 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.69 |
| ▸ | GSK3B | P49841 | 5/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12952883 | 0.91 | CDK2 (0.76) | CDK2CCNA2CCNA1CCNE1GSK3B | |
| SCHEMBL12952920 | 0.91 | CDK2 (0.70) | CDK2CCNA2CCNA1CCNE1GSK3B | |
| SCHEMBL12953226 | 0.91 | CDK2 (0.75) | CDK2CCNA2CCNA1CCNE1GSK3B | |
| SCHEMBL12953390 | 0.85 | CDK2 (0.70) | CDK2CCNA2CCNA1CCNE1GSK3B | |
| SCHEMBL12953220 | 0.85 | CDK2 (0.84) | CDK2CCNA2CCNA1CCNE1GSK3B | |
| SCHEMBL13116856 | 0.84 | CDK2 (0.66) | CDK2CCNA2CCNA1CCNE1GSK3B | |
| SCHEMBL12953832 | 0.83 | GSK3B (0.70) | CDK2CCNA2CCNA1CCNE1GSK3B | |
| SCHEMBL12953213 | 0.83 | CDK2 (0.65) | CDK2CCNA2CCNA1CCNE1GSK3B | |
| SCHEMBL13304832 | 0.82 | CDK2 (0.98) | CDK2CCNE1GSK3B | |
| SCHEMBL12953179 | 0.82 | CDK2 (0.80) | CDK2CCNA2CCNA1CCNE1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537116-B1 | PYRAZOLOPYRIMIDINES SUITABLE FOR THE TREATMENT OF CANCER DISEASES | SCHERING CORP (US) | 2010-06-02 | — | — | EP | disclosed |