Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 15/20 | 0.66 |
| ▸ | GSK3B | P49841 | 6/20 | 0.61 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13119482 | 0.93 | CDK2 (0.65) | CDK2GSK3BCCNE1CCNA2CCNA1 | |
| SCHEMBL13119457 | 0.92 | CDK2 (0.73) | CDK2GSK3BCCNE1CCNA2CCNA1 | |
| SCHEMBL13119500 | 0.89 | CDK2 (0.69) | CDK2GSK3BCCNE1CCNA2CCNA1 | |
| SCHEMBL13119477 | 0.89 | CDK2 (0.69) | CDK2GSK3BCCNE1CCNA2CCNA1 | |
| SCHEMBL13119374 | 0.88 | CDK2 (0.61) | CDK2GSK3BCCNE1CCNA2CCNA1 | |
| SCHEMBL13119340 | 0.86 | CDK2 (0.68) | CDK2GSK3BCCNE1CCNA2CCNA1 | |
| SCHEMBL13119499 | 0.86 | CDK2 (0.73) | CDK2GSK3BCCNE1CCNA2CCNA1 | |
| SCHEMBL13119521 | 0.86 | CDK2 (0.73) | CDK2GSK3BCCNE1CCNA2CCNA1 | |
| SCHEMBL13119510 | 0.86 | CDK2 (0.65) | CDK2GSK3BCCNE1CCNA2CCNA1 | |
| SCHEMBL13119451 | 0.86 | CDK2 (0.65) | CDK2GSK3BCCNE1CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537116-B1 | PYRAZOLOPYRIMIDINES SUITABLE FOR THE TREATMENT OF CANCER DISEASES | SCHERING CORP (US) | 2010-06-02 | — | — | EP | disclosed |