⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL30876995 | 0.93 | — | — | |
| Succinic Acid SCHEMBL1331059 | 0.77 | — | — | |
| Malonic Acid SCHEMBL7886847 | 0.75 | — | — | |
| SCHEMBL1363500 | 0.74 | — | — | |
| Adipic Acid SCHEMBL1332448 | 0.72 | — | — | |
| Bromoacetic Acid SCHEMBL1331191 | 0.72 | — | — | |
| Chloroacetic Acid SCHEMBL1332038 | 0.72 | — | — | |
| Pimelic Acid SCHEMBL13875811 | 0.69 | — | — | |
| SCHEMBL12396668 | 0.69 | — | — | |
| Propionic Acid SCHEMBL1331443 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112136043-B | Mass spectrometry method for detecting and quantifying liver function metabolites | 梅塔博隆股份有限公司 | 2024-03-22 | — | — | CN | claimed |
| US-20260034098-A1 | BRIDGED TRICYCLIC GABA DERIVATIVES AS CALCIUM CHANNEL MODULATORS, METHODS OF MAKING AND METHODS OF USING THEREOF | YICHANG HUMANWELL PHARMACEUTICALS CO., LTD. (CN) | 2026-02-05 | — | — | US | disclosed |
| US-20240415014-A1 | ORGANIC MOLECULE LIGHT EMITTERS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2024-12-12 | — | — | US | disclosed |
| CN-112136043-B | Mass spectrometry method for detecting and quantifying liver function metabolites | 梅塔博隆股份有限公司 | 2024-03-22 | — | — | CN | disclosed |
| US-11536726-B2 | Mass spectrometry assay method for detection and quantitation of liver function metabolites | METABOLON, INC. (US) | 2022-12-27 | — | — | US | disclosed |
| EP-3892602-A1 | METHOD FOR THE PREPARATION OF DEUTERATED OR TRITIATED COMPOUNDS | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2021-10-13 | — | — | EP | disclosed |
| US-20210148924-A1 | MASS SPECTROMETRY ASSAY METHOD FOR DETECTION AND QUANTITATION OF LIVER FUNCTION METABOLITES | METABOLON, INC. (US) | 2021-05-20 | — | — | US | disclosed |
| CN-107098899-B | The bicyclic azepine compound of M1 receptor stimulating agent as muscarine | 赫普泰雅治疗有限公司 | 2019-09-06 | — | — | CN | disclosed |
| US-10259802-B2 | Bicyclic aza compounds as muscarinic M1 receptor antagonists | HEPTARES THERAPEUTICS LIMITED (GB) | 2019-04-16 | — | — | US | disclosed |
| CN-109142577-A | The method and kit of metabolin in a kind of detection dried blood spot | 中国人民解放军总医院 | 2019-01-04 | — | — | CN | disclosed |
| US-9673030-B2 | Computer readable storage mediums, methods and systems for normalizing chemical profiles in biological or medical samples detected by mass spectrometry | EMORY UNIVERSITY (US) | 2017-06-06 | — | — | US | disclosed |
| US-9669013-B2 | Bicyclic aza compounds as muscarinic M1 receptor agonists | HEPTARES THERAPEUTICS LIMITED (GB) | 2017-06-06 | — | — | US | disclosed |
| CN-104640851-B | Bicyclic aza compounds as muscarinic M1 receptor agonists | 赫普泰雅治疗有限公司 | 2017-05-31 | — | — | CN | disclosed |
| EP-2897948-B1 | BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LTD (GB) | 2016-08-31 | — | — | EP | disclosed |
| US-20160128996-A1 | BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS | NXERA PHARMA UK LIMITED (GB) | 2016-05-12 | — | — | US | disclosed |
| US-9266857-B2 | Bicyclic AZA compounds as muscarinic M1 receptor agonists | HEPTARES THERAPEUTICS LIMITED (GB) | 2016-02-23 | — | — | US | disclosed |
| US-20150232443-A1 | BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS | NXERA PHARMA UK LIMITED (GB) | 2015-08-20 | — | — | US | disclosed |
| EP-2897948-A1 | BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS | Heptares Therapeutics Limited (GB) | 2015-07-29 | — | — | EP | disclosed |
| WO-2014045031-A1 | BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2014-03-27 | — | — | WO | disclosed |
| US-20110282587-A1 | COMPUTER READABLE STORAGE MEDIUMS, METHODS AND SYSTEMS FOR NORMALIZING CHEMICAL PROFILES IN BIOLOGICAL OR MEDICAL SAMPLES DETECTED BY MASS SPECTROMETRY | EMORY UNIVERSITY (US) | 2011-11-17 | — | — | US | disclosed |