SCHEMBL13308481

SCHEMBL13308481

Cc1ccc(C(Cc2ccc(N(c3ccc(C)cc3)c3ccc(CC(c4ccccc4)c4ccc(C)cc4)cc3)cc2)c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
CYP2C19 P33261 1/20 0.44
SLC6A3 Q01959 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
PSMB5 P28074 1/20 0.40
CNR2 P34972 5/20 0.38
CNR1 P21554 4/20 0.38
HTR2A P28223 2/20 0.37
HRH1 P35367 1/20 0.37
CYP19A1 P11511 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12346035 0.98 SLC6A2 (0.46) SLC6A2SLC6A4CYP2C19SLC6A3SMN1; SMN2
SCHEMBL23251188 0.97 SLC6A2 (0.44) SLC6A2SLC6A4CYP2C19SLC6A3SMN1; SMN2
SCHEMBL10633353 0.95 CYP2C19 (0.50) SLC6A2SLC6A4CYP2C19SLC6A3SMN1; SMN2
SCHEMBL14283625 0.92 CNR2 (0.48) CYP2C19MEN1KMT2ACNR2CNR1
SCHEMBL4973916 0.89 SLC6A2 (0.53) SLC6A2SLC6A4SLC6A3SMN1; SMN2MEN1
SCHEMBL14283648 0.88 CYP2C19 (0.66) CYP2C19CNR2CNR1
SCHEMBL14507112 0.87 SLC6A2 (0.52) SLC6A2SLC6A4CYP2C19SLC6A3MEN1
SCHEMBL10489055 0.87 SLC6A2 (0.55) SLC6A2SLC6A4SLC6A3SMN1; SMN2MEN1
SCHEMBL14283606 0.87 CNR2 (0.47) CYP2C19MEN1KMT2ACNR2CNR1
SCHEMBL24385493 0.85 SLC6A2 (0.41) SLC6A2SLC6A4CYP2C19SLC6A3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-20100150606-A1 METHOD OF MANUFACTURING IMAGE BEARING MEMBER, IMAGE BEARING MEMBER, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2010-06-17 US disclosed