SCHEMBL1330930

SCHEMBL1330930

COC1CCCCC(=O)O1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.41
CA1 P00915 3/20 0.40
CA9 Q16790 2/20 0.40
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 1/20 0.33
CYP2C19 P33261 2/20 0.31
CASP1 P29466 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP1A2 P05177 2/20 0.31
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11581842 0.98 CYP2D6 (0.40) CYP2D6CA1CA9CA2CA4
SCHEMBL11581762 0.94
SCHEMBL4777163 0.85
SCHEMBL292028 0.79 CA1 (0.36) CYP2D6CA1CA9CA2CA4
SCHEMBL11583470 0.77 CA1 (0.35) CYP2D6CA1CA9CA2CA4
SCHEMBL10963251 0.77 TSHR (0.36) CYP2D6CA1CA9CA2CA4
SCHEMBL7590787 0.72 CYP1A2 (0.44) KMT2AALDH1A1CYP1A2
SCHEMBL11581889 0.72 CA1 (0.38) CYP2D6CA1CA9CYP1A2
SCHEMBL18268933 0.71
SCHEMBL487396 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10836976-B2 Polymeric viscosity modifiers for use in lubricants AFTON CHEMICAL CORPORATION (US) 2020-11-17 US claimed
EP-1438368-B1 PHOTOCHROMIC POLYMERIZABLE COMPOSITIONS TRANSITIONS OPTICAL INC (US) 2008-02-20 EP claimed
US-6998072-B2 Containing polymerizable material and photochromic compound; ophthalmic lenses TRANSITIONS OPTICAL, INC. (US) 2006-02-14 US claimed
US-6916537-B2 Articles having a photochromic polymeric coating TRANSITIONS OPTICAL INC. (US) 2005-07-12 US claimed
EP-1451256-B1 ARTICLES HAVING A PHOTOCHROMIC POLYMERIC COATING TRANSITIONS OPTICAL INC (US) 2005-06-29 EP claimed
EP-1451256-A1 ARTICLES HAVING A PHOTOCHROMIC POLYMERIC COATING TRANSITIONS OPTICAL, INC. (US) 2004-09-01 EP claimed
EP-1438368-A1 PHOTOCHROMIC POLYMERIZABLE COMPOSITIONS TRANSITIONS OPTICAL, INC. (US) 2004-07-21 EP claimed
US-20030143404-A1 Articles having a photochromic polymeric coating TRANSITIONS OPTICAL LIMITED (IE) 2003-07-31 US claimed
US-20030136948-A1 Photochromic polymerizable compositions TRANSITIONS OPTICAL LIMITED (IE) 2003-07-24 US claimed
WO-2003038009-A1 PHOTOCHROMIC POLYMERIZABLE COMPOSITIONS TRANSITIONS OPTICAL, INC. (US) 2003-05-08 WO claimed
WO-2003037998-A1 ARTICLES HAVING A PHOTOCHROMIC POLYMERIC COATING TRANSITIONS OPTICAL, INC. (US) 2003-05-08 WO claimed
US-4963275-A POLYOLEFIN MODIFIED BY AN UNSATURATED ANHYDRIDE, THE REACTION PRODUCT OF A POLYAMINE AND ACRYLIC COMPOUND AND A LACTONE OR POLYLACTONE; OIL ADDITIVES EXXON CHEMICAL PATENTS INC. (US) 1990-10-16 US claimed
US-10836976-B2 Polymeric viscosity modifiers for use in lubricants AFTON CHEMICAL CORPORATION (US) 2020-11-17 US disclosed
EP-2471832-B1 METHOD FOR PRODUCING SOFT POLYURETHANE FOAM AND SEAT ASAHI GLASS CO LTD (JP) 2017-06-14 EP disclosed
US-9512266-B2 Process for organocatalytic ring-opening polymerization BASF SE (DE) 2016-12-06 US disclosed
EP-2739667-B1 METHOD FOR PRODUCING BRANCHED POLYETHERCARBONATES AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2016-03-30 EP disclosed
EP-0302643-A1 Lactone-modified mannich base dispersant additives useful in oleaginous compositions EXXON CHEMICAL PATENTS INC. (US) 1989-02-08 EP disclosed
EP-0263704-A2 Lactone modified, aminated dispersant additives useful in oleaginous compositions EXXON CHEMICAL PATENTS INC. (US) 1988-04-13 EP disclosed
EP-0263706-A2 Adducts or reactants modified with a lactone and oleaginous compositions containing same EXXON CHEMICAL PATENTS INC. (US) 1988-04-13 EP disclosed
US-4071507-A POLYMERIZATION STAMICARBON, N.V. (NL) 1978-01-31 US disclosed