Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.71 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.71 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.71 |
| ▸ | DRD3 | P35462 | 3/20 | 0.71 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | HTR1A | P08908 | 2/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.71 |
| ▸ | DRD1 | P21728 | 2/20 | 0.71 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.71 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | BCL2 | P10415 | 1/20 | 0.70 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13309489 | 1.00 | CYP2D6 (0.71) | CYP2D6KCNH2CHRM2ADRA2AADRA1A | |
| SCHEMBL6824843 | 1.00 | CYP2D6 (0.71) | CYP2D6KCNH2CHRM2ADRA2AADRA1A | |
| SCHEMBL16757326 | 0.92 | CYP2D6 (0.66) | CYP2D6KCNH2CHRM2ADRA2AADRA1A | |
| SCHEMBL7668121 | 0.90 | CHRM2 (0.83) | CYP2D6KCNH2CHRM2ADRA2AADRA1A | |
| SCHEMBL5267415 | 0.88 | CYP2D6 (0.68) | CYP2D6KCNH2CHRM2ADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL31327366 | 0.86 | CYP2D6 (0.65) | CYP2D6KCNH2CHRM2ADRA2AADRA1A | |
| SCHEMBL2054235 | 0.86 | CYP2D6 (0.67) | CYP2D6KCNH2CHRM2ADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL16107427 | 0.84 | CYP2D6 (0.64) | CYP2D6KCNH2CHRM2ADRA2AADRA1A | |
| SCHEMBL5363117 | 0.84 | CYP2D6 (0.76) | CYP2D6KCNH2CHRM2ADRA2AADRA1A | |
| Homochlorcyclizine SCHEMBL30402 | 0.84 | DRD3 (1.00) | CYP2D6KCNH2CHRM2ADRA2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100145049-A1 | PROCESS FOR MAKING N-(DIPHENYLMETHYL)PIPERAZINES | SYNTHON BV (NL) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145049-A1 | PROCESS FOR MAKING N-(DIPHENYLMETHYL)PIPERAZINES | IL5, PRMT5, IL15 | CYP2D6 547/4885KCNH2 683/4885CHRM2 513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.