Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 8/20 | 0.64 |
| ▸ | LYPLA1 | O75608 | 4/20 | 0.60 |
| ▸ | LYPLA2 | O95372 | 4/20 | 0.60 |
| ▸ | PRKCA | P17252 | 3/20 | 0.55 |
| ▸ | PLA2G6 | O60733 | 2/20 | 0.55 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.55 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | PRKCG | P05129 | 1/20 | 0.51 |
| ▸ | PRKCB | P05771 | 1/20 | 0.51 |
| ▸ | PRKCH | P24723 | 1/20 | 0.51 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.51 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.51 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 6/20 | 0.47 |
| ▸ | PNLIP | P16233 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16540894 | 1.00 | DAGLA (0.64) | DAGLALYPLA1LYPLA2PRKCAPLA2G6 | |
| SCHEMBL714006 | 1.00 | DAGLA (0.64) | DAGLALYPLA1LYPLA2PRKCAPLA2G6 | |
| SCHEMBL712929 | 1.00 | DAGLA (0.64) | DAGLALYPLA1LYPLA2PRKCAPLA2G6 | |
| SCHEMBL715056 | 1.00 | DAGLA (0.64) | DAGLALYPLA1LYPLA2PRKCAPLA2G6 | |
| SCHEMBL10073515 | 1.00 | DAGLA (0.64) | DAGLALYPLA1LYPLA2PRKCAPLA2G6 | |
| SCHEMBL19576215 | 0.96 | DAGLA (0.69) | DAGLALYPLA1LYPLA2PRKCAPLA2G6 | |
| SCHEMBL16617219 | 0.96 | DAGLA (0.69) | DAGLALYPLA1LYPLA2PRKCAPLA2G6 | |
| SCHEMBL21679661 | 0.96 | DAGLA (0.69) | DAGLALYPLA1LYPLA2PRKCAPLA2G6 | |
| SCHEMBL21679665 | 0.96 | DAGLA (0.69) | DAGLALYPLA1LYPLA2PRKCAPLA2G6 | |
| SCHEMBL21679663 | 0.96 | DAGLA (0.69) | DAGLALYPLA1LYPLA2PRKCAPLA2G6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728153-B2 | Method for the asymmetric synthesis of beta-lactone compounds | THE BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-06-01 | — | — | US | disclosed |