Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006650 | 0.91 | MAPK1 (0.65) | MAPK1KMT2AMEN1HRH3MAPT | |
| SCHEMBL9669207 | 0.85 | MAPK1 (0.56) | MAPK1KMT2AMEN1HRH3MAPT | |
| SCHEMBL3504393 | 0.85 | MAPK1 (0.56) | MAPK1KMT2AMEN1HRH3MAPT | |
| SCHEMBL17197259 | 0.84 | MAPK1 (0.54) | MAPK1KMT2AMEN1HRH3MAPT | |
| SCHEMBL31316090 | 0.84 | MAPK1 (0.54) | MAPK1KMT2AMEN1HRH3MAPT | |
| SCHEMBL17197305 | 0.84 | MAPK1 (0.54) | MAPK1KMT2AMEN1HRH3MAPT | |
| SCHEMBL21610968 | 0.83 | ESR1 (0.63) | MAPK1KMT2AMEN1HRH3MAPT | |
| SCHEMBL19002254 | 0.82 | MAPK1 (0.57) | MAPK1KMT2AMEN1HRH3MAPT | |
| SCHEMBL21661732 | 0.82 | ESR1 (0.52) | MAPK1KMT2AMEN1HRH3MAPT | |
| SCHEMBL19068970 | 0.82 | ESR2 (0.60) | MAPK1KMT2AMEN1HRH3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727976-B2 | Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs | XENOPORT, INC. (US) | 2010-06-01 | — | — | US | disclosed |