Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 3/20 | 1.00 |
| ▸ | F3 | P13726 | 3/20 | 1.00 |
| ▸ | MMP2 | P08253 | 2/20 | 1.00 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | ECE1 | P42892 | 1/20 | 1.00 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 1.00 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 1.00 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | BID | P55957 | 7/20 | 0.95 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.95 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.95 |
| ▸ | BAK1 | Q16611 | 6/20 | 0.95 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.84 |
| ▸ | EP300 | Q09472 | 3/20 | 0.84 |
| ▸ | KAT5 | Q92993 | 3/20 | 0.84 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5370295 | 1.00 | F7 (1.00) | F7F3MMP2SAE1KDM4E | |
| SCHEMBL5394786 | 1.00 | F7 (1.00) | F7F3MMP2SAE1KDM4E | |
| SCHEMBL5370300 | 1.00 | F7 (1.00) | F7F3MMP2SAE1KDM4E | |
| Ginkgolic Acid 17:1 SCHEMBL5380765 | 1.00 | F7 (1.00) | F7F3MMP2SAE1KDM4E | |
| Gingkolic Acid SCHEMBL163525 | 1.00 | F7 (1.00) | F7F3MMP2SAE1KDM4E | |
| Ginkgolic Acid 17:1 SCHEMBL5380767 | 1.00 | F7 (1.00) | F7F3MMP2SAE1KDM4E | |
| Ginkgolic Acid 17:1 SCHEMBL5380775 | 1.00 | F7 (1.00) | F7F3MMP2SAE1KDM4E | |
| Gingkolic Acid SCHEMBL8040660 | 1.00 | F7 (1.00) | F7F3MMP2SAE1KDM4E | |
| SCHEMBL5370293 | 1.00 | F7 (1.00) | F7F3MMP2SAE1KDM4E | |
| Gingkolic Acid SCHEMBL8042802 | 1.00 | F7 (1.00) | F7F3MMP2SAE1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728043-B2 | Methods for treatment of beta-amyloid protein-induced ocular disease | KIM DARRICK S H L | 2010-06-01 | — | — | US | disclosed |
| US-20070003641-A1 | Synergistic pharmaceutical compositions useful in prevention and treatment of beta-amyloid protein-induced disease | KIM DARRICK S H | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070003641-A1 | Synergistic pharmaceutical compositions useful in prevention and treatment of beta-amyloid protein-induced disease | APP, BACE1, GSAP | F7 4476/4885F3 3129/4885MMP2 2237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.