Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13339552 | 0.93 | SMN1; SMN2 (0.38) | SMN1; SMN2HPGDHTTALDH1A1USP2 | |
| SCHEMBL13311688 | 0.88 | SMN1; SMN2 (0.35) | SMN1; SMN2HPGDHTTALDH1A1USP2 | |
| SCHEMBL13339536 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDHTTALDH1A1DRD2 | |
| SCHEMBL277686 | 0.83 | SMN1; SMN2 (0.39) | SMN1; SMN2HPGDHTTALDH1A1USP2 | |
| SCHEMBL18264887 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDHTTALDH1A1USP2 | |
| SCHEMBL25100480 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2HPGDHTTALDH1A1USP2 | |
| SCHEMBL13339558 | 0.80 | POLB (0.33) | SMN1; SMN2HPGDHTTUSP2FOLH1 | |
| SCHEMBL14864100 | 0.80 | HPGD (0.43) | SMN1; SMN2HPGDHTTALDH1A1DRD2 | |
| SCHEMBL2607938 | 0.80 | HTT (0.43) | SMN1; SMN2HPGDHTTALDH1A1DRD2 | |
| SCHEMBL13167176 | 0.80 | TSHR (0.36) | HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137511-A1 | POLYMER FACTOR IX MOIETY CONJUGATES | NEKTAR THERAPEUTICS (US) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137511-A1 | POLYMER FACTOR IX MOIETY CONJUGATES | F9, F13A1, F8 | SMN1; SMN2 2365/4885HPGD 1255/4885HTT 2131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.