Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | HLCS | P50747 | 2/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | IDE | P14735 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14524254 | 0.94 | TDP1 (0.46) | TDP1CNR1HLCSFOLH1CAPN1 | |
| SCHEMBL13311889 | 0.93 | TDP1 (0.53) | TDP1FOLH1CAPN1MEN1ABL1 | |
| SCHEMBL14524259 | 0.90 | TDP1 (0.55) | TDP1CNR1FOLH1CAPN1MEN1 | |
| SCHEMBL13311902 | 0.90 | TDP1 (0.55) | TDP1CNR1FOLH1CAPN1MEN1 | |
| SCHEMBL14524258 | 0.90 | TDP1 (0.58) | TDP1CNR1FOLH1CAPN1MEN1 | |
| SCHEMBL13311899 | 0.90 | TDP1 (0.58) | TDP1CNR1FOLH1CAPN1MEN1 | |
| SCHEMBL13311891 | 0.88 | TDP1 (0.56) | TDP1CNR1FOLH1CAPN1MEN1 | |
| SCHEMBL14524253 | 0.87 | TDP1 (0.47) | TDP1FOLH1CAPN1MEN1ABL1 | |
| SCHEMBL13311855 | 0.86 | TDP1 (0.51) | TDP1CNR1FOLH1CAPN1MEN1 | |
| SCHEMBL13311913 | 0.84 | TDP1 (0.58) | TDP1CNR1FOLH1CAPN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160210-A1 | GUANIDINIUM DELIVERY CARRIERS | NITTO DENKO CORPORATION (JP) | 2010-06-24 | — | — | US | disclosed |
| US-20070078094-A1 | Guanidinium delivery carriers | NITTO DENKO CORPORATION (JP) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160210-A1 | GUANIDINIUM DELIVERY CARRIERS | SLC2A9, SLC29A2, SLC2A4 | TDP1 1606/4885CNR1 1239/4885HLCS 665/4885 |
| US-20070078094-A1 | Guanidinium delivery carriers | SLC2A9, SLC29A2, SLC2A4 | TDP1 1606/4885CNR1 1239/4885HLCS 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.