Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 8/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10021107 | 0.85 | PTGER2 (0.41) | PTGER2PTGER3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13232169 | 0.85 | PTGER2 (0.41) | PTGER2PTGER3LMNAALDH1A1HPGD | |
| SCHEMBL3402623 | 0.83 | PTGER2 (0.45) | PTGER2PTGER3LMNA | |
| SCHEMBL317580 | 0.81 | PTGER2 (0.38) | PTGER2PTGER3 | |
| SCHEMBL14368236 | 0.74 | OPRL1 (0.48) | PTGER2PTGER3LMNA | |
| SCHEMBL13232170 | 0.74 | PTGER2 (0.46) | PTGER2PTGER3TP53ALDH1A1CYP3A4 | |
| SCHEMBL10021104 | 0.74 | PTGER2 (0.46) | PTGER2PTGER3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13423049 | 0.74 | PTGER2 (0.43) | PTGER2PTGER3 | |
| SCHEMBL13695429 | 0.73 | PTGER2 (0.36) | PTGER2PTGER3LMNA | |
| SCHEMBL318512 | 0.73 | PTGER2 (0.41) | PTGER2PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732443-B2 | Therapeutic substituted cyclopentanes | ALLERGAN, INC. | 2010-06-08 | — | — | US | disclosed |
| US-7427685-B2 | Therapeutic substituted cyclopentanes | ALLERGAN, INC. (US) | 2008-09-23 | — | — | US | disclosed |