Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 19/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 19/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 19/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3427485 | 1.00 | ADORA2A (0.61) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL13296391 | 1.00 | ADORA2A (0.61) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL14357694 | 0.90 | ADORA2A (0.48) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL3428302 | 0.88 | ADORA2A (0.61) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL13296393 | 0.88 | ADORA2A (0.61) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL13314257 | 0.88 | ADORA2A (0.61) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL14148777 | 0.88 | ADORA2A (0.53) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL3425443 | 0.87 | ADORA2A (0.66) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL13314261 | 0.87 | ADORA2A (0.66) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL13296396 | 0.87 | ADORA2A (0.66) | ADORA2AADORA3ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737127-B2 | 2-propynyl adenosine analogs having A2A agonist activity and compositions thereof | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2010-06-15 | — | — | US | disclosed |