Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3547809 | 1.00 | KCNH2 (0.49) | KCNH2SLC2A1 | |
| SCHEMBL3548360 | 0.88 | KCNH2 (0.63) | KCNH2SLC2A1 | |
| SCHEMBL14386284 | 0.81 | KCNH2 (0.64) | KCNH2 | |
| SCHEMBL3547140 | 0.81 | KCNH2 (0.64) | KCNH2 | |
| SCHEMBL3543479 | 0.80 | KCNH2 (0.76) | KCNH2 | |
| SCHEMBL3549818 | 0.79 | KCNH2 (0.70) | KCNH2SLC2A1 | |
| SCHEMBL13839752 | 0.78 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL3544976 | 0.77 | KCNH2 (0.58) | KCNH2SLC2A1 | |
| SCHEMBL3543685 | 0.77 | KCNH2 (0.61) | KCNH2SLC2A1 | |
| Hydrochloric Acid SCHEMBL3550429 | 0.77 | KCNH2 (0.57) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732461-B2 | (4S)-4-({4-[(2,3-Dihydro[1,4]dioxino[2,3-c]pyridin-7-ylmethyl)amino]-1-piperidinyl}methyl)-3-fluoro-4-hydroxy-4,5-dihydro-7H-pyrrolo[3,2,1-de]-1,5-naphthyridin-7-one, used in the treatment of bacterial infections caused by a wide range of organisms including both gramnegative and grampositive bacteria | GLAXO GROUP LIMITED (GB) | 2010-06-08 | — | — | US | disclosed |
| US-7732461-B2 | (4S)-4-({4-[(2,3-Dihydro[1,4]dioxino[2,3-c]pyridin-7-ylmethyl)amino]-1-piperidinyl}methyl)-3-fluoro-4-hydroxy-4,5-dihydro-7H-pyrrolo[3,2,1-de]-1,5-naphthyridin-7-one, used in the treatment of bacterial infections caused by a wide range of organisms including both gramnegative and grampositive bacteria | GLAXO GROUP LIMITED (GB) | 2010-06-08 | — | — | US | disclosed |