Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 18/20 | 0.86 |
| ▸ | ADRA1A | P35348 | 9/20 | 0.86 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13315551 | 0.95 | MCHR1 (0.85) | MCHR1ADRA1AOPRL1 | |
| SCHEMBL13315511 | 0.93 | MCHR1 (1.00) | MCHR1ADRA1AOPRL1 | |
| SCHEMBL13315592 | 0.91 | MCHR1 (0.82) | MCHR1ADRA1AOPRL1 | |
| SCHEMBL13315602 | 0.91 | MCHR1 (1.00) | MCHR1ADRA1AOPRL1 | |
| SCHEMBL13315590 | 0.91 | MCHR1 (0.90) | MCHR1ADRA1AOPRL1 | |
| SCHEMBL13315557 | 0.91 | MCHR1 (0.80) | MCHR1ADRA1A | |
| SCHEMBL13315529 | 0.90 | MCHR1 (0.96) | MCHR1ADRA1AOPRL1 | |
| SCHEMBL13315553 | 0.90 | MCHR1 (0.82) | MCHR1ADRA1AOPRL1 | |
| SCHEMBL13315554 | 0.89 | MCHR1 (0.80) | MCHR1ADRA1A | |
| SCHEMBL13315581 | 0.89 | MCHR1 (0.69) | MCHR1ADRA1AOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727998-B2 | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| US-7727998-B2 | Melanin-concentrating hormone receptor antagonists containing piperidine derivatives as the active ingredient | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |