Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | IL6ST | P40189 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 2/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 5/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671341 | 0.86 | PPARA (0.43) | PPARAIL6STFAAHNAAAIDH1 | |
| SCHEMBL3782697 | 0.86 | PPARA (0.43) | PPARAIL6STFAAHNAAAIDH1 | |
| SCHEMBL3782695 | 0.86 | PPARA (0.43) | PPARAIL6STFAAHNAAAIDH1 | |
| SCHEMBL17221991 | 0.86 | PPARA (0.43) | PPARAIL6STFAAHNAAAIDH1 | |
| SCHEMBL13316603 | 0.86 | PPARA (0.43) | PPARAIL6STFAAHNAAAIDH1 | |
| SCHEMBL23829979 | 0.85 | PPARA (0.43) | PPARAIL6STFAAHNAAAIDH1 | |
| SCHEMBL17222138 | 0.85 | PPARA (0.43) | PPARAIL6STFAAHNAAAIDH1 | |
| SCHEMBL17222139 | 0.85 | PPARA (0.43) | PPARAIL6STFAAHNAAAIDH1 | |
| SCHEMBL6068526 | 0.84 | PPARA (0.43) | PPARAIL6STFAAHNAAAIDH1 | |
| SCHEMBL6068528 | 0.84 | PPARA (0.43) | PPARAIL6STFAAHNAAAIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745459-B2 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-06-29 | — | — | US | disclosed |
| US-7745459-B2 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-06-29 | — | — | US | disclosed |